Trimethylol aminomethane hydrochloride (Tris-HCl) is used for protein crystal growth at different pH conditions. The low ionic strength of Tris-HCL buffer can be used for the formation of intermediate fibers of lamin in C. legans. Tris-HCl is also one of the main components of protein electrophoresis buffer. In addition, Tris-HCL is also an intermediate for the preparation of surfactants, vulcanization accelerators and some drugs (see related literature)