2 ', 3-dimethyl-N -[5-(2-pyrazinyl) -2-pyridyl]-[2,4 '-bipyridyl] -5-acetamide is a chemical known by its alias LGK974 or WNT974. It is a potent, orally active, specific Porcupine(PORCN) inhibitor with an IC50 value of 0.1nM. In addition, the compound has been used as an investigational drug to study the mechanisms of tumorigenesis and progression (see related literature)
