Berberine is an antibacterial drug, which has antibacterial effect on hemolytic streptococcus, Staphylococcus aureus, gonococcus, Fredricki and Shigella dysenteriae, and can enhance white blood cell phagocytosis, and inhibit tuberculosis bacillus and yersinia pestis to varying degrees. Widely used in the treatment of gastroenteritis, bacillary dysentery, tuberculosis, scarlet fever, acute tonsillitis and respiratory infections also have a certain effect. Chinese medicine uses Coptis, Phellodendri, Sanzhi needle and ten fruits as heat-clearing and detoxification drugs, among which the main active ingredient is berberine (refer to relevant literature)