CAS No.: 2140-46-7
Molecular formula: C27H46O2
Molecular weight: 402.65
Biological activity: 25-Hydroxycholesterol is a metabolite of cholesterol, which is produced and secreted by macrophages in response to the activation of Toll-like receptor (TLR). 25-Hydroxycholesterol effectively and selectively inhibits the production of IgA by B cells, EC50 is about 65nM.