CAS No.: 606-68-8

Molecular formula: C21H30N7NaO14P2

Molecular weight: 689.44

Introduction: Nicotinamide adenine dinucleotide (reduced coenzyme I) is a coenzyme that transmits protons (more accurately, hydrogen ions), which appears in many metabolic reactions of cells. NADH or more accurate NADH+H+is its reduction form. It can be reduced, carrying at most two protons (written as NADH+H+).

Use: beta-nicotinamide adenine dinucleoside disodium is a biologically active form of nicotinic acid. Coenzyme used as hydrogenase and dehydrogenase. NAD usually acts as a hydrogen receptor, forms NADH, and then acts as a hydrogen donor in the respiratory chain. It mainly exists in living cells in the form of reduction (NADPH) and participates in the synthesis reaction. There are two forms, α- NAD and β- NAD, which is characterized by the configuration of ribosyl nicotinamide bond. only β- Heterosomes have biological activity.

Physiological function: coenzyme, which is important in human redox reaction, appears in many metabolic reactions of cells. As an essential coenzyme for biocatalytic reactions, it participates in thousands of physiological reactions, such as cell tricarboxylic acid cycle (TCA), fat β Oxidation is of great significance in the metabolism and utilization of sugar, fat, amino acid and other nutrients. It is also the sole substrate of coenzyme I consuming enzymes (such as NAD+dependent ADP ribosyltransferase). These enzymes decompose coenzyme I (NAD+) as substrate into ADP ribose and nicotinamide (Nam), and play different physiological functions in different cells, such as participating in DNA repair, cell oxidative pressure regulation and other physiological functions.