CAS No.: 41753-43-9

Molecular formula: C54H92O23

Molecular weight: 1109.29

Overview: Ginsenoside Rb1 is a panaxadiol saponin, belonging to damarane type triterpenoid saponin compound, mainly distributed in the plants of acanthopanax ginseng, panax notoginseng, panax quinquefolium and other plants. It has many pharmacological activities, such as anti-aging, anti-cerebral ischemia injury, promoting peripheral nerve cell regeneration, improving learning and memory function, anti-tumor, hypoglycemic, improving sexual function, anti-stress, etc., especially in the central nervous system, cardiovascular system The immune system and anti-tumor, anti-liver warm ischemia reperfusion, anti-myocardial ischemia reperfusion, anti-lung ischemia reperfusion have good medicinal value.

Physical and chemical properties: white amorphous powder or colorless crystal, slightly sweet and bitter taste, hygroscopic, generally unstable to acid, can be hydrolyzed under weak acid, but can not get the true prototype saponin after hydrolysis. It is soluble in water, methanol and ethanol, soluble in n-butanol, acetic acid and ethyl acetate, and insoluble in ether and benzene. It is optically active and mostly dextral. Strong foam is produced by shaking the aqueous solution.

Physiological function: China's "Shennong Baicao Classic" summarizes the medicinal value of ginseng as: strengthening the body and mind, calming the nerves, stopping palpitation, brightening the eyes, and prolonging life if taken for a long time. In recent years, research has found that ginsenoside is the main bioactive component of ginseng, which can be divided into panaxadiol type, panaxatriol type and oleanolic acid type according to chemical structure, and more than 40 kinds have been isolated. Among them, ginsenoside Rb1 is the focus of current research, and is one of the representative components of panaxadiol saponins. It belongs to damarane type triterpenoid saponins, which are easily soluble in water, ethanol and methanol. It is mainly distributed in the plants of acanthopanax ginseng, panax notoginseng, panax quinquefolium and other plants. It is their main active ingredient and has a variety of biological activities.