CAS No.: 15291-77-7

Molecular formula: C20H24O10

Molecular weight: 424.4

Ginkgo biloba extract: Ginkgolide B is a diterpenoid lactone compound extracted from the roots and dry leaves of Ginkgo biloba, a plant of Ginkgo biloba family. It is easily soluble in ethyl acetate, methanol, ethanol, dimethyl sulfoxide and other solvents. The molecule contains multiple reducing hydroxyl functional groups, which can directly remove and capture free radicals, inhibit the formation of harmful substances such as MDA, and has obvious anti-lipid peroxidation damage effect, thus delaying aging. At the same time, it has a specific antagonistic effect on platelet activating factor (PAF). Ginkgolide A, Ginkgolide B, Ginkgolide C and Ginkgolide M contain a series of bitter diterpenoid lactones in the leaves and roots of Ginkgo biloba; Among them, ginkgolide B has the strongest active physiological activity and is the strongest platelet activating factor antagonist found so far. It can be used in the clinical treatment of thrombus, acute pancreatitis and cardiovascular disease, and also in the treatment of metastatic cancer. It also has protective effects on injured neurons, as well as anti-oxidation and anti-aging effects. Ginkgolide b injection is a new type of intravenous injection of traditional chinese medicine, which has a single and clear composition, significant curative effect, good safety and high market acceptance. Ginkgolide b injection is mainly used to dissipate phlegm and remove blood stasis, and unblock the pulse and collaterals. It is used to treat the syndrome of phlegm and blood stasis blocking collaterals of ischemic stroke. Ginkgolide A has a significant preventive effect on stress ulcer, has a recovery effect on cholinergic damage memory function, can prevent the decrease of ChAT activity, alleviate and improve myocardial ischemia, can inhibit the occurrence of DAD, and has an anti-anxiety effect.

Pharmacological effect: Among ginkgolides, ginkgolide B has the strongest active physiological activity and is the strongest platelet activating factor antagonist found so far. It can be used in the clinical treatment of thrombus, acute pancreatitis and cardiovascular diseases, and also in the treatment of metastatic cancer. It also has protective effects on injured neurons, and has antioxidant and anti-aging effects.